Comparison of anthropometric indices for the screening of nonalcoholic fatty liver disease in pre- and postmenopausal women.

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Abstract:

OBJECTIVES:Although it has been well-established that menopause causes a shift in body fat, there has been no study conducted yet to examine the best obesity parameters to predict the risk of nonalcoholic fatty liver disease (NAFLD) in this population. Thus, the aim of this study was to clarify the superiority among various obesity indices such as body mass index (BMI), waist circumference (WC), and waist-to-hip ratio (WHR) for predicting NAFLD in pre- and postmenopausal women. METHODS:This cross-sectional analysis included 620 healthy women (318 premenopausal and 302 postmenopausal women) between 20 and 80 years of age recruited from the Health Promotion Center of Korea University Guro Hospital. NAFLD was diagnosed by abdominal ultrasonography. RESULTS:In premenopausal women, there were no statistical differences in the area under the curve values among the three obesity indices, whereas, in postmenopausal women, the area under the curve value of WHR was significantly larger than those of either BMI (difference between area: 0.102, 95% confidence interval: 0.031, 0.173) or WC (difference between area: 0.064, 95% confidence interval: 0.018-0.109). Furthermore, in postmenopausal women, the combination of WHR with BMI or WC significantly increased predictive power of NAFLD when compared to using BMI or WC alone. The optimal cutoff values for BMI, WC, and WHR for detecting NAFLD were 23.9 kg/m, 69 cm, and 0.81 in premenopausal women and 22.9 kg/m, 74 cm, and 0.86 in postmenopausal women, respectively. CONCLUSIONS:In premenopausal women, BMI, WC, and WHR hold similar potential in predicting the risk of NAFLD, whereas, in postmenopausal women, WHR is the most useful discriminative indicator for NAFLD. Women's optimal cutoff values for NAFLD were different according to menopausal status.

绝经前后妇女非酒精性脂肪肝筛查的人体测量指标比较。

c

摘要:

目标: 尽管已经确定更年期会导致身体脂肪的转移, 目前还没有研究检查最佳肥胖参数来预测该人群中非酒精性脂肪性肝病 (NAFLD) 的风险。因此,本研究的目的是阐明各种肥胖指标如体重指数 (BMI) 、腰围 (WC) 、和腰臀比 (WHR) 预测绝经前和绝经后妇女 NAFLD。 方法: 该横断面分析包括从韩国大学 Guro 医院健康促进中心招募的 620 名年龄在 20-80 岁之间的健康妇女 (318 名绝经前妇女和 302 名绝经后妇女)。经腹部超声检查诊断为 NAFLD。 结果: 在绝经前妇女中,3 种肥胖指标的曲线下面积值无统计学差异,而在绝经后妇女中, 腰臀比曲线下面积明显大于 BMI (面积间差异: 0.102,95% 置信区间: 0.031,0.173)或 WC (面积之差: 0.064,95% 置信区间: 0.018-0.109)。此外,在绝经后妇女中,与单独使用 BMI 或 WC 相比,WHR 与 BMI 或 WC 的组合显著增加了 NAFLD 的预测能力。BMI 、 WC 和 WHR 检测 NAFLD 的最佳临界值为绝经前妇女 23.9 kg/m 、 69 cm 和 0.81,22.9 kg/m 、 74 cm。和 0.86 分别在绝经后妇女。 结论: 在绝经前妇女中,BMI 、 WC 和 WHR 在预测 NAFLD 风险方面具有相似的潜力,而在绝经后妇女中,WHR 是 NAFLD 最有用的判别指标。根据绝经状态,女性 NAFLD 的最佳截断值不同。

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MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY

研究方向:医学-妇产科学
IF:2.953
IF值的bai意思是影响因子。是汤森路透(duThomson Reuters)出品的期刊引证报告zhi(Journal Citation Reports,JCR)中的一项数据。 影响因子dao目前的计算方法是:IF=C/(M+N)。以2017年IF的计算为例,M为该期刊2015年发表的文章数量,N为该期刊2016年发表的文章数量,C为该期刊2015和2016年两年发表的文章在2017年这一年被引用的
出版周期: UNITED STATES
中科院分区:Q4 来稿接收率:约 % 审稿周期:一般,3-8周
18.70%
YES
1994
1072-3714
出版地区: CiteScore:
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MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY 期刊简介

英文简介:

Menopause: The Journal of The North American Menopause Society publishes articles of importance in this rapidly expanding area of interest to specialists, general practitioners, nurses, and social workers. It features peer-reviewed, original research papers and review articles related to menopause, hormone replacement therapy, nonhormone and hormone-related aging factors in women, cardiovascular disease in women, osteoporosis, breast cancer and other female cancers, and primary-preventive health care for women in the perimenopausal period.

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中文简介

更年期:《北美更年期协会杂志》发表了许多重要的文章,引起了专家、全科医生、护士和社会工作者的兴趣。它的特点是同行评审,原始的研究论文和评论文章有关更年期,激素替代疗法,非激素和激素相关的老化因素的妇女,心血管疾病的妇女,骨质疏松症,乳腺癌和其他女性癌症,以及初级预防保健妇女在围绝经期。

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MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY期刊中科院评价数据

最新中科院JCR分区

大类(学科) 小类(学科) 学科排名
医学 OBSTETRICS & GYNECOLOGY(产科医学和妇科医学) 3区
24/82

最新公布的期刊年发文量

年度总发文量 年度论文发表量 年度综述发表量
161 150 11

总被引频次: 5517

特征因子: 0.008220

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MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY期刊CiteScore评价数据

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文献(2015-2017)

=

次引用

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被引比率: %

SJR:
SCLmago期刊等级衡量经过加权后的期刊受引用次数,引用次数的加权值由施引期刊的学科领域和声望(SJR)决定。
SNIP:
每篇文章中来源出版物的标准化影响将实际受引用情况对照期刊所属学科领域中预期的受引用情况进行衡量。
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