Objectively-Measured Activity Patterns are Associated with Home Blood Pressure in Memory Clinic Patients.

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Abstract:

BACKGROUND:Physicians are cautious to prescribe antihypertensive drugs in frail older adults because of the potential adverse effects, especially in those with cognitive complaints. Lifestyle aspects might provide safe targets to lower blood pressure in older adults. OBJECTIVE:Our goal was to evaluate the associations between activity patterns and blood pressure in memory clinic patients. METHODS:We used an observational cross-sectional study to measure activity patterns with the ActivPAL accelerometer, and simultaneous home blood pressure levels in memory clinic patients (age range 51-87 years old). Office blood pressure was assessed during routine clinical practice. RESULTS:41 patients (mean age of 74.3 (7.7) years of age, 46% female) were included. Sedentary parameters were associated with higher mean home blood pressure, with the strongest correlation between more prolonged sitting bouts and higher SBP (r = 0.58, p < .0001). Physical activity parameters were negatively associated with mean home blood pressure. Adjusted regression estimates remained significant, showing, e.g., a 4.5 (95% CI = 1.6;7.4) mmHg increase in SBP for every hour of sitting per day and a -1.0 (95% CI = -1.8;-0.2) mmHg decrease in DBP for every additional 1000 steps per day. No strong correlations were found between any of the activity pattern variables and office blood pressure. CONCLUSION:Associations between activity pattern variables and blood pressure were only found with home blood pressure measurements, not with office measurements. Longitudinal evaluations of these associations are now needed to explore if reducing prolonged sedentary bouts and increasing step count indeed serve as safe targets to lower blood pressure.

客观测量的活动模式与记忆门诊患者的家庭血压相关。

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摘要:

背景: 由于潜在的不良反应,特别是那些有认知主诉的患者,内科医生谨慎地给虚弱的老年人开降压药。生活方式方面可能为老年人降低血压提供安全目标。 目的: 我们的目标是评估记忆门诊患者活动模式与血压之间的相关性。 方法: 我们采用一项观察性横断面研究,用 ActivPAL 加速度计测量活动模式,并在记忆门诊患者 (年龄范围 51-87 岁) 中同时测量家庭血压水平。在常规临床实践期间评估办公室血压。 结果: 共纳入 41 例患者 (平均年龄 74.3 (7.7) 岁,46% 为女性)。久坐参数与较高的平均家庭血压相关,久坐和较高的 SBP 之间的相关性最强 (r = 0.58,p

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JOURNAL OF ALZHEIMERS DISEASE

研究方向:医学-神经科学
IF:4.671
IF值的bai意思是影响因子。是汤森路透(duThomson Reuters)出品的期刊引证报告zhi(Journal Citation Reports,JCR)中的一项数据。 影响因子dao目前的计算方法是:IF=C/(M+N)。以2017年IF的计算为例,M为该期刊2015年发表的文章数量,N为该期刊2016年发表的文章数量,C为该期刊2015和2016年两年发表的文章在2017年这一年被引用的
出版周期: NETHERLANDS
中科院分区:Q4 来稿接收率:约 % 审稿周期:平均2月
11.70%
YES
1998
1387-2877
出版地区: CiteScore:

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JOURNAL OF ALZHEIMERS DISEASE 期刊简介

英文简介:

Published by IOS Press. ISSN: 1387-2877. The Journal of Alzheimer's Disease is an international multidisciplinary journal to facilitate progress in understanding the etiology, pathogenesis, epidemiology, genetics, behavior, treatment and psychology of Alzheimer's disease. The journal publishes research reports, reviews, short communications, book reviews, and letters-to-the-editor. The journal is dedicated to providing an open forum for original research that will expedite our fundamental understanding of Alzheimer's disease.

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中文简介

由IOS出版社出版。ISSN: 1387 - 2877。 《阿尔茨海默病杂志》是一份国际性的多学科期刊,旨在促进对阿尔茨海默病的病因、发病机制、流行病学、遗传学、行为、治疗和心理学的理解。该杂志出版研究报告、评论、简短的交流、书评和给编辑的信件。该杂志致力于为原始研究提供一个开放的论坛,将加快我们对阿尔茨海默病的基本认识。

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JOURNAL OF ALZHEIMERS DISEASE期刊中科院评价数据

最新中科院JCR分区

大类(学科) 小类(学科) 学科排名
医学 NEUROSCIENCES(神经系统科学) 3区
96/261

最新公布的期刊年发文量

年度总发文量 年度论文发表量 年度综述发表量
736 660 76

总被引频次: 20383

特征因子: 0.041470

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JOURNAL OF ALZHEIMERS DISEASE期刊CiteScore评价数据

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被引比率: %

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SCLmago期刊等级衡量经过加权后的期刊受引用次数,引用次数的加权值由施引期刊的学科领域和声望(SJR)决定。
SNIP:
每篇文章中来源出版物的标准化影响将实际受引用情况对照期刊所属学科领域中预期的受引用情况进行衡量。
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