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Abstract:
Studies regarding the association between anxiety disorders and obstetrical and neonatal complications are inconclusive and sometimes contradictive. The aim of the present study was to assess perinatal outcome of mothers with anxiety disorder and to determine the association between maternal anxiety and long-term neuropsychiatric hospitalizations of the offspring. A hospital-based retrospective cohort study was conducted, comparing pregnancy complications and long-term neuropsychiatric hospitalizations of offspring of mothers with anxiety disorder, during or before the pregnancy and mothers without anxiety. All singleton deliveries between the years 1991 and 2014 in a tertiary medical center were included. To evaluate perinatal outcome of women with anxiety disorders, generalized estimation equation (GEE) models were used to control for confounders. A Kaplan-Meier survival curve was used to compare cumulative incidence of long-term neuropsychiatric hospitalizations, and a Cox proportional hazards model was constructed to control for confounders. During the study period, 242,038 deliveries met the inclusion criteria, of them 0.1% (n = 304) were mothers with anxiety. Using GEE models, controlling for maternal age, maternal anxiety was noted as an independent risk factor for preterm delivery (adjusted OR 1.8, 95% CI 1.32-2.69; P < 0.001), hypertensive disorders (adjusted OR 1.7, 95% CI 1.08-2.69; P = 0.02) and cesarean delivery (adjusted OR 1.6, 95% CI 1.32-2.1; P < 0.001). Offspring born to mothers with anxiety disorders had higher rates of neuropsychiatric-related hospitalizations (6.3 vs 3.1% P = 0.002; Kaplan-Meier log-rank test P < 0.001). Using a Cox proportional hazards model, controlling for confounders such as maternal age, hypertensive disorders, gestational age, birth weight, and cesarean delivery, being born to a mother with anxiety disorders was found to be an independent risk factor for long-term neuropsychiatric hospitalizations of the offspring (adjusted HR 2.4, 95% CI 1.58-3.89; P < 0.001). Pregnancy of women with anxiety disorders is independently associated with adverse perinatal outcome and higher risk for long-term neuropsychiatric hospitalizations of the offspring.
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最新影响因子:4.405 | 期刊ISSN:1434-1816 | CiteScore: |
出版周期:Quarterly | 是否OA:YES | 出版年份:1998 |
期刊官方网址:http://www.springer.com/medicine/psychiatry/journal/737
自引率:7.30% | 研究方向:医学-精神病学 |
出版地区:AUSTRIA |
SCI期刊coverage:Science Citation Index Expanded(科学引文索引扩展)
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The relationship between mental disorders and reproductive functions in women has fascinated scientific thinkers for centuries. Nevertheless it has been well documented that sex and gender differences in mental illness and their treatment are understudied until now. In many cases the role of the obstetric-gynecologic event or condition in the psychiatric illness is not recognized: Many women have questions and concerns about psychiatric aspects of menstruation and menopause. Feelings about hysterectomy or the loss or termination of a pregnancy may play a role in the dynamics of a current conflict. Many manias depressions and other psychoses are related to endocrinology. Sexual abuse is a frequent feature of the history of patients with several major psychiatric disorders. Current developments in reproductive technology are new challenges for psychiatrists as well. The editors of "Archives of Women's Mental Health" hope that this journal will assist clinicians teachers and researchers to incorporate knowledge of all aspects of women's mental health into current and future clinical care and research. The journal's scope includes psychodynamics social and biological aspects of all psychiatric and psychosomatic disorders in women. The editors especially welcome interdisciplinary studies focussing on the interface between psychiatry psychosomatics obstetrics and gynecology. The exchange of knowledge between psychiatrists and obstetrician-gynecologists is one of the major aims of the journal. "Archives of Women's Mental Health" publish rigorously reviewed research papers short original communications case reports review articles book reviews and letters to the editors on psychiatric and psychosomatic disorders in women related to the menstrual cycle pregnancy childbirth and perimenopause psychiatric aspects of childloss and abortion sterilization and perimenopause maternal mental illness and disorders of mother-to-infant attachment and all other aspects of motherhood and mental health gender differences in psychopathology psychopharmacology and epidemiology of psychiatric disorders psychotropic drugs and the safety of their use during pregnancy and breastfeeding the association between ovarian hormones and neurochemistry and other biological aspects of psychiatric disorders in women psychosocial cultural and ethnic aspects of psychiatric disorders in women psychiatric aspects of domestic violence liaison psychiatry in women's hospital planning specialized mental health services for women hormonal treatment of psychiatric disorders related to women's reproductive system influence of menstrual cycle on pharmacokinetics of psychotropic drugs psychological aspects of cancer in women sexual disorders in women alcohol and drug abuse in the practic
几个世纪以来,女性的精神障碍和生殖功能之间的关系一直吸引着科学思想家。然而,到目前为止,关于精神疾病及其治疗的性别和性别差异的研究还很不够。在许多情况下,妇产科事件或条件在精神疾病中的作用没有得到承认:许多妇女对月经和更年期的精神方面有疑问和担忧。对子宫切除或失去或终止妊娠的感觉可能在当前冲突的动态中发挥作用。许多躁狂、抑郁和其他精神疾病都与内分泌学有关。性虐待是几个主要精神疾病患者历史上的一个常见特征。目前生殖技术的发展对精神病学家来说也是新的挑战。《妇女心理健康档案》的编辑们希望这本杂志能帮助临床医生、教师和研究人员将妇女心理健康的各个方面的知识纳入当前和未来的临床护理和研究。该杂志的范围包括心理动力学,社会和生物学方面的所有精神和心身疾病的妇女。编辑们特别欢迎跨学科的研究集中在精神病学、心理医学、产科和妇科之间的接口。精神科医生和妇产科医生之间的知识交流是该杂志的主要目的之一。“女性的心理健康档案”发布严格的审查研究论文原始通讯案例报告综述文章短书评和信件编辑的相关精神和心身障碍的女性月经周期妊娠分娩和准更年期精神病方面的childloss堕胎和绝育和准更年期孕产妇精神疾病和紊乱的母婴依恋母亲和精神的和所有其他方面健康性别差异在精神病理学精神药理学和精神疾病流行病学精神药品和他们在怀孕和哺乳期间使用的安全卵巢激素和神经化学之间的关系和其他精神疾病的生物方面女性心理精神障碍的文化和种族方面女性家庭暴力的精神方面联络精神病学在女子医院规划专业心理健康为女性激素治疗相关精神障碍的女性生殖系统影响月经周期,药物代谢动力学,精神药物,心理方面的女性癌症,女性性功能障碍,酒精和药物滥用的实践
大类(学科) | 小类(学科) | 学科排名 |
医学 |
PSYCHIATRY (精神病学) 3区 |
66/142 |
年度总发文量 | 年度论文发表量 | 年度综述发表量 |
85 | 74 | 11 |
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研究方向:医学 精神病学
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发表一篇学和医学成像类SCI论文
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