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Abstract:
OBJECTIVES:To estimate the systemic serious adverse event (SAE) rates after colonoscopy and to identify their risk factors. METHODS:A nationwide cohort study was conducted using the comprehensive French claims databases SNDS (National Health Data System). Patients aged 30 years and over who underwent a first screening or diagnostic colonoscopy in 2010-2015 were included. The rates of cardiovascular and renal SAEs were estimated within 5 days after colonoscopy. The standardized incidence ratios were calculated to compare these incidence rates with those of the same events in the general population, and the associated risk factors were assessed by multilevel logistic regression. RESULTS:Among the 4,088,799 included patients (median age, 59 years [interquartile range = 50-67]; 55.2% women; 30.1% with a Charlson index score ≤1), the 5-day SAE incidence rate was 2.8/10,000 procedures for shock, 0.87/10,000 for myocardial infarction, 1.9/10,000 for stroke, 2.9/10,000 for pulmonary embolism, 5.5/10,000 for acute renal failure, and 3.3/10,000 for urolithiasis. These SAEs occurred 3.3 to 15.8 times more often during the first 5 days after colonoscopy than expected in the general population. Thirty-day mortality rates ranged from 2.2/1,000 cases of urolithiasis to 268.1/1,000 cases of shock. Increasing age was associated with an increasing incidence of SAEs. Risks of shock and acute renal failure were associated with a greater number of comorbidities than the other SAEs. Colonoscopies in university hospitals were associated with higher risks, reflecting patient selection processes. DISCUSSION:The systemic SAEs can be associated with a substantial mortality. They should be taken into account when deciding colonoscopy, in addition to perforation and bleeding, particularly in elderly patients with multiple comorbidities.
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最新影响因子:12.045 | 期刊ISSN:0002-9270 | CiteScore:4.52 |
出版周期:Monthly | 是否OA:YES | 出版年份:1954 |
自引率:4.50% | 研究方向:医学-胃肠肝病学 |
出版地区:UNITED STATES |
SCI期刊coverage:Science Citation Index Expanded(科学引文索引扩展)
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The American Journal of Gastroenterology presents the latest clinically oriented information in the field of gastroenterology, including manuscripts, case reports, papers presented before the annual convention and postgraduate course of the American College of Gastroenterology.
《美国胃肠病学杂志》提供了胃肠病学领域最新的临床导向信息,包括手稿、病例报告、在年会前发表的论文以及美国胃肠病学学院的研究生课程。
大类(学科) | 小类(学科) | 学科排名 |
医学 |
GASTROENTEROLOGY & HEPATOLOGY (胃肠肝病学) 2区 |
6/80 |
年度总发文量 | 年度论文发表量 | 年度综述发表量 |
145 | 118 | 27 |
引文计数(2018)
文献(2015-2017)
5208次引用
1151篇文献
序号 | 类别 | 排名 | 百分位 |
1 |
大类(学科):Medicine
小类(学科):Hepatology
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#5/59
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2 |
大类(学科):Medicine
小类(学科):Gastroenterology
|
#6/128
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审稿时间: 2个月内 接受率: 比较困难(25%命中)
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ISSN:0026-1394
研究方向:工程技术-物理:应用
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影响因子:1.446
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影响因子:8.307
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研究方向:CHEMISTRY, MULTIDISCIPLINARY-NANOSCIENCE & NANOTEC
影响因子:6.739
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研究方向:CHEMISTRY, MULTIDISCIPLINARY-NANOSCIENCE & NANOTEC
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研究方向:CHEMISTRY, MULTIDISCIPLINARYMATERIALS SCIE-MATERIA
影响因子:2.024
ISSN:1745-8080
研究方向:工程技术-材料科学:综合
发表一篇学和医学成像类SCI论文
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