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Abstract:
BACKGROUND:Evidence-based guidelines recommend that von Willebrand factor (VWF) levels be obtained in the third trimester of pregnancy to facilitate peripartum planning for women with von Willebrand disease (VWD). OBJECTIVES:To identify the frequency of third trimester monitoring in a nationally representative sample of pregnant women with VWD in the United States, as well as the frequency of reproductive bleeding after pregnancy. PATIENTS/METHODS:Patient data were obtained from the Truven Health MarketScan Research Databases. International Classification of Diseases-9 codes were used to identify women with VWD and evidence of infant delivery. We defined third trimester monitoring as a laboratory claim for VWF levels during the 3 months before delivery. Clinical outcomes studied included postpartum hemorrhage (PPH) and heavy menstrual bleeding (HMB). RESULTS:We identified 2238 unique pregnant females with VWD. Of these, 32% (n = 714) underwent third-trimester testing of VWF levels. Diagnostic codes consistent with PPH were recorded for 6.5% of women in the 6 weeks after infant delivery. The frequency of PPH in women who underwent VWF monitoring (4.9%) was significantly lower than in those who did not undergo monitoring (7.3%), (risk difference -2.4%, 95% CI -4.4% to -0.3%, P = .023). Diagnostic codes consistent with HMB were recorded for 4.7% of women in the 3 months after infant delivery. CONCLUSIONS:Third-trimester VWF monitoring was associated with a lower risk of PPH, but testing was performed in only one-third of insured pregnant women with VWD in the United States despite expert recommendations.
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最新影响因子:16.036 | 期刊ISSN:1538-7933 | CiteScore:3.8 |
出版周期:Monthly | 是否OA:YES | 出版年份:2003 |
期刊官方网址:http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1538-7836
自引率:7.70% | 研究方向:医学-外周血管病 |
出版地区:ENGLAND |
SCI期刊coverage:Science Citation Index Expanded(科学引文索引扩展)
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The mission of the new Journal of Thrombosis and Haemostasis will be to advance science related to the important medical problems of thrombosis, bleeding disorders and vascular biology through the diffusion and exchange of information and ideas within the international research community. The Journal publishes high quality, original research reports, state-of-the art reviews, invited commentary and debate on timely topics, letters and announcements. Editors invite both laboratory and clinical reports. The Journal of Thrombosis and Haemostasis is now available in print and online.
新一期《血栓与止血》杂志的使命是通过在国际研究领域内传播和交流信息和思想,促进与血栓形成、出血障碍和血管生物学等重要医学问题有关的科学。该杂志出版高质量的原创研究报告,最新的技术评论,邀请评论和辩论及时的主题,信件和公告。编辑邀请实验室和临床报告。《血栓与止血杂志》现已出版,并可在线阅读。
大类(学科) | 小类(学科) | 学科排名 |
医学 |
HEMATOLOGY (血液学) 2区 PERIPHERAL VASCULAR DISEASE (外周血管病) 2区 |
14/71 7/65 |
年度总发文量 | 年度论文发表量 | 年度综述发表量 |
243 | 226 | 17 |
引文计数(2018)
文献(2015-2017)
3861次引用
1015篇文献
序号 | 类别 | 排名 | 百分位 |
1 |
大类(学科):Medicine
小类(学科):Hematology
|
#16/120
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研究方向:医药科学 血液系统 出血 凝血 血栓
影响因子:6.497
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ISSN:1540-2002
研究方向:CLINICAL NEUROLOGY-PSYCHIATRY
影响因子:4.562
ISSN:0269-8811
研究方向:医学-精神病学
影响因子:6.533
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研究方向:医学-精神病学
影响因子:5.415
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研究方向:医学-精神病学
影响因子:2.493
ISSN:0925-4927
研究方向:医学-精神病学
发表一篇学和医学成像类SCI论文
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