发表一篇学和医学成像类SCI论文
需要多少钱?
Abstract:
:Osteosarcoma (OS) is the most common primary malignant bone tumor worldwide. Recently, several studies have shown that the long non-coding RNA (lncRNA) CDKN2B-AS1 plays a critical role in several cancers. However, the function and underlying mechanism of CDKN2B-AS1 in OS development remains elusive. In this study, we firstly assessed the expression of CDKN2B-AS1 in OS tissues and cells, showing that CDKN2B-AS1 expression were remarkably upregulated in OS tissues and cells. Moreover, CDKN2B-AS1 knockdown suppressed cell proliferation, migration, and EMT progress in OS. Interestingly, we found and proved that CDKN2B-AS1 could sponge miR-4458 in OS cells. Moreover, MAP3K3 was certified as a downstream target of miR-4458 in OS. Besides, MAP3K3 was negatively regulated by miR-4458 and positively regulated by CDKN2B-AS1. More importantly, overexpression of MAP3K3 could partly counteract the effect of CDKN2B-AS1 suppression on the biological behavior of OS cells. Also, the in vivo experiments further testified that CDKN2B-AS1 accelerated tumor growth in OS. Our results suggested that CDKN2B-AS1 facilitated OS progression by sponging miR-4458 to enhance MAP3K3 expression, which provides a novel insight into improving diagnostic and therapeutic strategies for patients with OS.
展开更多
最新影响因子:2.723 | 期刊ISSN:1071-2690 | CiteScore:N/A |
出版周期:Bimonthly | 是否OA:YES | 出版年份:0 |
期刊官方网址:http://www.springer.com/life+sciences/cell+biology/journal/11626
自引率:5.70% | 研究方向:生物-发育生物学 |
出版地区:UNITED STATES |
SCI期刊coverage:Science Citation Index Expanded(科学引文索引扩展)
专业编辑在线一对一答疑及时解决您的问题
Founded in 1965, In Vitro Cellular & Developmental Biology - Animal remains unique in its focus on in vitro biology in animals. This peer-reviewed journal reports results of research in cellular, molecular, and developmental biology that employ or are relevant to organs, tissue, tumors, and cells in vitro. Coverage includes biotechnology; cell and tissue models; cell growth, differentiation, apoptosis; cellular pathology/virology; cytokines/growth factors/adhesion factors; signal transduction; toxicology/chemical carcinogenesis; product applications and more. With its high-caliber original research and reviews, In Vitro Cellular & Developmental Biology - Animal benefits everyone who needs to keep up-to-date on the latest developments and state-of-the-art research in animal cell and tissue culture and biotechnology from around the world. A journal of the Society for In Vitro Biology (SIVB).
成立于1965年,在体外细胞和发育生物学-动物仍然是独特的,其重点在体外生物学的动物。本同行评审的杂志报告了细胞、分子和发育生物学的研究结果,这些研究采用或与体外器官、组织、肿瘤和细胞相关。覆盖范围包括生物技术;细胞和组织模型;细胞生长、分化、凋亡;细胞病理学/病毒学;细胞因子和生长因子/粘附的因素;信号转导;毒理学/化学致癌;产品应用和更多。 其高水平的原始研究和评论,在体外细胞和发育生物学-动物受益的每一个人都需要保持最新的发展和最先进的研究动物细胞和组织培养和生物技术从世界各地。 体外生物学会(SIVB)期刊。
大类(学科) | 小类(学科) | 学科排名 |
生物 |
CELL BIOLOGY (细胞生物学) 4区 DEVELOPMENTAL BIOLOGY (发育生物学) 4区 |
172/190 36/42 |
年度总发文量 | 年度论文发表量 | 年度综述发表量 |
104 | 99 | 5 |
引文计数(2018)
文献(2015-2017)
N/A次引用
N/A篇文献
序号 | 类别 | 排名 | 百分位 |
1 |
大类(学科):Pharmacology, Toxicology and Pharmaceutics
小类(学科):Toxicology
|
#0/111
点击查看排名表
|
|
推荐刊物均可到国家新闻出
版总署网站查询正刊
可签署保密协议 ,不透露任
何用户信息可跟踪进程,全程
协议
1对1服务,7x24小时在线
15年经验沉淀,实体公司
运营
影响因子:43.474
ISSN:1074-7613
研究方向:医学-免疫学
影响因子:2.957
ISSN:0891-6934
研究方向:医学-免疫学
影响因子:3.152
ISSN:0171-2985
研究方向:医学-免疫学
影响因子:4.04
ISSN:1750-743X
研究方向:医学-免疫学
影响因子:3.594
ISSN:1471-2172
研究方向:医学-免疫学
影响因子:2.211
ISSN:0198-8859
研究方向:医学-免疫学
影响因子:31.25
ISSN:1529-2908
研究方向:医学-免疫学
影响因子:4.23
ISSN:0165-2478
研究方向:医学-免疫学
影响因子:8.701
ISSN:1933-0219
研究方向:医学-免疫学
发表一篇学和医学成像类SCI论文
需要多少钱?
专注医学期刊服务15年
您好:请问您咨询什么等级的期刊?专注医学类期刊发表15年口碑企业,为您提供以下服务:
1.医学核心期刊发表-全流程服务
2.医学SCI期刊-全流程服务
3.论文投稿服务-快速报价
4.期刊推荐直至录用,不成功不收费
客服正在输入...
IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL 投稿经验
(由下方点评分析获得,0人参与,5206人阅读)