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The Journal of nutrition 妊娠期钠摄入量,而不是其他旨在预防心血管疾病的饮食建议,与妊娠期高血压疾病的风险呈正相关。
影响因子:4.687 DOI:10.1093/jn/nxz197
作者: Arvizu M,Bjerregaard AA,Madsen MTB,Granström C,Halldorsson TI,Olsen SF,Gaskins AJ,Rich-Edwards JW,Rosner BA,Chavarro JE 发表时间:2020-02-03 02:59:27
keywords: Arvizu MBjerregaard AAMadsen MTBGranström CHalldorsson TIOlsen SFGaskins AJRich-Edwards JWRosner BAChavarro JE
关键词: AHA 2020 目标 破折号 饮食模式 妊娠期高血压 先兆子痫 妊娠
Abstract
BACKGROUND:The role of diet on hypertensive disorders of pregnancy (HDPs), including preeclampsia and gestational hypertension (GHTN), remains unclear. OBJECTIVES:We evaluated whether adherence during pregnancy to dietary recommendations that reduce cardiovascular disease (CVD) in the general population is related to the risk of HDPs. METHODS:We followed 66,651 singleton pregnancies from 62,774 women participating in the Danish National Birth Cohort. Diet was assessed during week of gestation 25 with an FFQ from which we created 2 dietary pattern scores: 1) AHA, based on the diet recommendations from the AHA 2020 Strategic Impact Goals; and 2) the Dietary Approaches to Stop Hypertension (DASH) diet. Cases of HDPs were identified through linkage with the Danish National Patient Registry. RRs and 95% CIs of HDPs were estimated by increasing quintiles of adherence to the AHA and DASH scores using log-Poisson regression models with generalized estimating equations-to account for repeated pregnancies per woman-while adjusting for potential confounders. Results: We identified 1809 cases of HDPs: n = 1310 preeclampsia (n = 300 severe preeclampsia) and n = 499 cases of GHTN. Greater adherence to AHA or DASH scores was not related to the risk of HDPs. However, when each component of the scores was separately evaluated, there were positive linear relations of sodium intake with HDPs (Plinearity < 0.01). Women with the highest sodium intake [median 3.70 g/d (range: 3.52, 7.52 g/d)] had 54% (95% CI:16%,104%) higher risk of GHTN and 20% (95% CI:1%, 42%) higher risk of preeclampsia than women with the lowest intake [median 2.60 g/d (range: 0.83, 2.79 g/d)]. In addition, intake of whole grains was positively related to the risk of GHTN but not to preeclampsia ( P-heterogeneity = 0.002). Conclusion: Sodium intake during pregnancy, but no other diet recommendations to prevent CVD among nonpregnant adults, is positively related to the occurrence of HDPs among pregnant Danish women. J Nutr 2019;00:1–8.
摘 要
背景: 饮食对妊娠期高血压疾病 (HDPs),包括子痫前期和妊娠期高血压 (GHTN) 的作用仍不清楚。 目的: 我们评估了在一般人群中,孕期对减少心血管疾病 (CVD) 的饮食建议的依从性是否与 HDPs 的风险相关。 方法: 我们对参加丹麦国家出生队列的 66,651 名妇女的 62,774 例单胎妊娠进行了随访。在妊娠 25 周期间使用 FFQ 评估饮食,我们从中创建了 2 个饮食模式评分: 1) AHA,基于 AHA 2020 战略影响目标的饮食建议; 和 2) 停止高血压 (DASH) 饮食的饮食方法。通过与丹麦国家患者登记处的联系确定了 HDPs 病例。使用具有广义估计方程的 log-Poisson 回归模型,通过增加 AHA 和 DASH 评分的五分位数来估计 HDPs 的 RRs 和 95% ci,以解释每个女性的重复妊娠-同时调整对于潜在的混杂因素。 结果: 我们确定了 1809 例 HDPs: n = 1310 的子痫前期 (n = 300 的重度子痫前期) 和 n = 499 的病例。较高的 AHA 或 DASH 评分依从性与 HDPs 风险无关。然而,当单独评估评分的每个组成部分时,钠摄入量与 HDPs 呈正相关线性关系 (单位线性
期刊介绍
《JOURNAL OF NUTRITION》 (点击进入期刊详情)
英文简介 : The premier journal in its field, The Journal of Nutrition continues to have as its goal the publication of papers based on original nutrition research in humans and other animal species. In circulation since 1928, it is the official monthly publication of the American Society for Nutritional Sciences. It is distributed to more than 4,500 subscribers worldwide. The Journal publishes original research reported by authors in over 30 countries. To provide expert evaluation of the many areas of nutrition research, the editorial office is assisted by scientists who serve as Associate Editors, Regional Correspondents, editorial board members and ad-hoc reviewers chosen for their nutritional science expertise. They provide constructive evaluation and fair and rapid editorial processing. Reports of research on the following and other areas of nutrition research are published: Animal Nutrition, Carbohydrates and Fibers, Community and International Nutrition, Diet and Disease, Energy and Macronutrient Metabolism, Growth and Development, Human Nutrition, Lipids, Maternal and Infant Nutrition, Metabolism and Hormonal Regulation, Neuroscience and Nutrition, Nutrient-Gene Interactions, Nutrient Metabolism, Nutrition and Immunology, Nutrition, Pharmacology and Toxicology, Nutritional Epidemiology, Proteins and Amino Acids, Public Health Nutrition and Policy, Vitamins and Minerals.
中文简介 : (来自Google、百度翻译) 《营养学杂志》是该领域的首要期刊,其目标仍然是发表基于人类和其他动物物种的原始营养学研究的论文。自1928年起发行,它是美国营养科学学会的官方月刊。它被分发到全球4500多个用户。该杂志发表了30多个国家的作者所报道的原始研究。为了对营养研究的许多领域进行专家评估,编辑部由科学家协助,这些科学家担任副编辑、区域通讯员、编辑委员会成员以及因其营养科学专业知识而选定的特设评审员。他们提供建设性的评估和公平、快速的编辑处理。发表了以下和其他营养研究领域的研究报告:动物营养、碳水化合物和纤维、社区和国际营养、饮食和疾病、能量和大营养代谢、生长和发育、人类营养、脂类、母婴营养、代谢和激素调节、神经系统和神经系统。科学与营养、营养基因相互作用、营养代谢、营养与免疫学、营养、药理学与毒理学、营养流行病学、蛋白质与氨基酸、公共卫生营养与政策、维生素与矿物质。
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