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Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 膳食抗氧化剂、氧化应激标志物、腹型肥胖与多囊性卵巢综合征的相关性: 一项病例对照研究。

影响因子：1.226 DOI：10.1080/01443615.2019.1603215

作者： Shahrokhi SA,Naeini AA 发表时间：2020-07-10 12:45:32

from：《JOURNAL OF OBSTETRICS AND GYNAECOLOGY》

keywords： Shahrokhi SANaeini AA

关键词：

Abstract

:In this case-control study, 60 patients with Polycystic ovary syndrome (PCOS) referred to the Nursing and Midwifery Center of Khorramabad, were selected as the case group and 90 non-PCOS patients as the control group. Demographic information and anthropometric indices of each person were collected. The Food Frequency Questionnaire (FFQ) and International Physical Activity Questionnaire (IPAQ) were completed. After at least 12 h of fasting, 7 mL of blood samples were taken from the patients. There was no statistically significant difference observed in the mean of the total antioxidant capacity (TAC) between the two groups. However, a statistically significant difference was found between the two groups in terms of malondialdehyde (MDA) and some dietary antioxidants levels (mean in case group: vit C = 34/2 mg, vit E = 7/7 mg, Se = 84/6 µg, Zn = 7/5 mg, beta-carotene = 762/8 µg, mean in control group: vit C = 72/5 mg, vit E = 10/6 mg, Se = 91/0 µg, Zn = 10/6 mg, beta-carotene = 1609/5 µg).IMPACT STATEMENTWhat is already known on this subject? Polycystic ovary syndrome (PCOS) is one of the most common endocrine abnormalities and is considered as the main cause of infertility. Some studies have evaluated the link between dietary intakes and oxidative stress markers in PCOS patients. It is well known that about 40-50% of individuals with PCOS are obese and that leads to an increase in lipid catabolism and production of free radicals and oxidative stress.What the results of this study add? The aim of the present study was to compare the level of dietary antioxidants and oxidative stress markers including TAC, MDA and abdominal obesity prevalence in PCOS patients with healthy individuals.What the implications are of these findings for clinical practice and/or further research? We hope that our study can be influential in the field of PCOS. Furthermore, our findings have indicated a statistically significant difference between the two groups in terms of MDA and some dietary antioxidants levels. This result might be encouraging in using antioxidant in patients with PCOS.

摘要

: 在这项病例对照研究中，60 例多囊卵巢综合征 (PCOS) 患者转诊到Khorramabad护理和助产中心，选择 90 例非PCOS患者作为对照组。收集每个人的人口统计学信息和人体测量指数。完成食物频率问卷 (FFQ) 和国际体力活动问卷 (IPAQ)。禁食至少 12 h后，抽取患者血样 7 ml。两组间总抗氧化能力 (TAC) 的平均值无统计学显著差异。然而，在丙二醛 (MDA) 和一些膳食抗氧化剂水平方面，两组之间存在统计学显著差异 (病例组平均值: vit c = 34/2 mg，vit e = 7/7 mg，Se = 84/6 µ g，Zn = 7/5 µ mg，β-胡萝卜素 = 762/8 µ g，对照组平均值: vit c = 72/5 µ mg，Vit e = 10/6 mg，Se = 91/0 µ g，Zn = 10/6 µ g，β-胡萝卜素 = 1609/5 µ g)。IMPACT statementing关于这个问题已经知道了什么？多囊卵巢综合征 (PCOS) 是最常见的内分泌异常之一，被认为是不孕的主要原因。一些研究评估了PCOS患者饮食摄入和氧化应激标志物之间的联系。众所周知，大约 40-50% 的PCOS个体是肥胖的，这导致脂质分解代谢和自由基的产生以及氧化应激的增加。这项研究的结果补充了什么？本研究的目的是比较PCOS患者与健康人的膳食抗氧化剂和氧化应激标志物水平，包括TAC、MDA和腹型肥胖患病率。这些发现对临床实践和/或进一步研究有什么意义？我们希望我们的研究能在PCOS领域产生影响。此外，我们的研究结果表明，在MDA和一些膳食抗氧化剂水平方面，两组之间存在统计学显著差异。这一结果在PCOS患者中使用抗氧化剂可能是令人鼓舞的。

期刊介绍

《JOURNAL OF OBSTETRICS AND GYNAECOLOGY》 (点击进入期刊详情)

英文简介 : Journal of Obstetrics and Gynaecology represents an established forum for the entire field of obstetrics and gynaecology, publishing a broad range of original, peer-reviewed papers, from scientific and clinical research to reviews relevant to practice. It also includes occasional supplements on clinical symposia. The journal is read widely by trainees in our specialty and we acknowledge a major role in education in Obstetrics and Gynaecology. Past and present editors have recognized the difficulties that junior doctors encounter in achieving their first publications and spend time advising authors during their initial attempts at submission. The journal continues to attract a world-wide readership thanks to the emphasis on practical applicability and its excellent record of drawing on an international base of authors.

中文简介 : （来自Google、百度翻译）妇产科学杂志是妇产科学和妇产科学领域的一个成熟的论坛，出版了从科学和临床研究到与实践相关的评论等一系列原创的、经过同行评审的论文。它还包括临床研讨会上偶尔的补充。该杂志被我们专业的学员广泛阅读，我们承认在产科和妇科教育中发挥着重要作用。过去和现在的编辑都认识到初级医生在完成他们的第一份出版物时遇到的困难，并在他们最初投稿时花时间向作者提供建议。由于强调实用性和它在吸收国际作者方面的优秀记录，该杂志继续吸引着全世界的读者。

CIRCULATION RESEARCH 期刊中科院评价数据

新中科院分区

大类(学科)	小类(学科)	学科排名
医学	OBSTETRICS & GYNECOLOGY (妇产科学)	78/82

新发布的期刊年发文量

年度总发文量	年度论文发表量	年度综述发表量
262	254	8

总被引频次 :2414

特征因子 : 0.002850

影响因子趋势图

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