翼状胬肉不同术式后巩膜溶解的观察分析

目的:比较翼状胬肉两种不同手术方式后巩膜溶解的发生概率,探讨产生巩膜溶解的原因,选择合理手术方式.方法:对本院两年来263例翼状胬肉采用两种不同的手术方式,观察术后发生巩膜溶解的情况,并通过局部药物进行治疗.结果:263例翼状胬肉患者,130例采用胬肉切除+结膜瓣转位术,裸露角膜缘3 mm巩膜,术后局部滴0.02％丝裂霉素C(mitomycin C,MMC),胬肉复发26例,发生巩膜溶解6例;133例采用胬肉切除+角膜缘干细胞移植术,术后滴0.02％ MMC,胬肉复发5例,无1例发生巩膜溶解.结论:翼状胬肉术后发生巩膜溶解,是一种严重的手术并发症,可能与术中过度烧灼巩膜面,巩膜板层暴露于MMC有关.采用胬肉切除+角膜缘干细胞移植术,植片覆盖裸露巩膜,促进巩膜表层愈合,术后避免MMC直接浸润巩膜板层故未见此并发症发生.与传统手术方式相比,复发率低,并发症少,是一种安全、有效的翼状胬肉手术方式.

Prevalence of intermittent exotropia among primary and secondary school students in Shantou, China

口服25％葡萄糖减轻早产儿眼底检查疼痛的研究

目的:探讨口服25％葡萄糖减轻早产极低出生体重儿在第一次早产儿视网膜病眼底检查时的疼痛的效果.方法:选取2014年9月至2015年8月在广东省妇幼保健院NICU住院的早产极低出生体重儿,随机分为观察组和对照组,观察组在进行第一次早产儿视网膜病眼底检查前2 min,给予25％葡萄糖溶液1 mL口服;对照组未用任何安慰剂.两组患儿眼底检查后分别进行新生儿疼痛量表的评估.结果:观察组患儿眼底检查后疼痛评分低于对照组(P＜0.001).结论:眼底检查前2 min口服25％葡萄糖溶液1 mL是缓解早产儿视网膜病检查引起的疼痛的有效措施.

Long term changes of posterior corneal elevation after myopic laser in situ keratomileusis

Optical coherence tomography angiography in wet age-related macular degeneration (AMD)

Over the last decades,substantial developments in retinal imaging offered a paradigmatic change in the understanding of the pathophysiology of wet age-related macular degeneration (AMD).

The way forward for big data analysis in ophthalmology and medicine

It was the best of times;it was the worst of times.It was the season of population medicine;it was the season of personalized medicine—or was it? Charles Dickens' fictional depiction of late eighteenth century France walked a tense line that masterfully narrated the untenable socioeconomic disparity of its day.He described the forces that inevitably led to the French revolution.Today in the world of medicine we are on the verge of similar untenable tension.

Inflammatory choroidal neovascularization after tubercular posterior scleritis

Professor Jian Ge: the road to the success of scientific research

Professor Jian Ge (Figure 1) currently is member of standing committee of the Asia Pacific Glaucoma Society,Honorary Chairman of the Chinese Ophthalmologic Society,Vice chairman of the Chinese Eye Doctor Association,Former Chairman of the Chinese Glaucoma Society,Honorary Lifetime Director of State Key Laboratory of Ophthalmology,Chairman of Guangdong Eye Doctor Association,member of standing committee of the Evidence-Based Medicine Committee of the Chinese Doctor Association,Editor-in-Chief of Eye Science and Molecular Vision,Vice Editor-in-Chief of Chinese Journal of Ophthalmology and Chinese Journal of Experimental Ophthalmology.

雷珠单抗和曲安奈德治疗视网膜中央静脉阻塞的黄斑水肿的配对病例研究

目的:研究玻璃体腔注射曲安奈德(triamcinolone acetonide,TA)和雷珠单抗(Lucentis)治疗视网膜中央静脉阻塞(central retinal vein occlusion,CRVO)的黄斑水肿的疗效.方法:配对病例对照研究.将2013年1月至2015年6月,在我院因CRVO并发黄斑水肿而接受玻璃体腔注射TA或Lucentis 的患者,根据患者基线水平的佳矫正视力(best-corrected visual acuity,BCVA) (logMAR视力)和黄斑中心厚度(central macular thickness,CMT)将两组患者进行配对,选出12对患者,主要的观察指标为随访1年时两组患者的BCVA和CMT.结果:TA组患者的BCVA由基线时的0.78±0.12提高到0.55±0.24(P=0.005),CMT由基线时的(598.92±192.67) μm减少到(258.28±75.38) μm (P=0.002).Lucentis组患者的BCVA由基线时的0.78±0.11提高到0.48±0.21 (P=0.002),CMT由基线时的(591.75±181.68) μm减少到(281.17±63.08) μm (P=0.002).TA组和Lucentis组患者基线及终的BCVA和CMT直接均无显著差异.TA组的平均注药次数为(2.4±0.9)次,Lucentis组为(4.0±1.6)次,两组有统计学差异(P=0.012).结论:玻璃体腔注射TA或Lucentis均能减轻CRVO所致的黄斑水肿并提高视力,两者的疗效并无显著差异.TA的平均注射次数比Lucentis组少,但是TA更容易引起眼压升高.应该根据患者的综合情况制定个性化的治疗方案.

青光眼视神经保护的相关分析及研究进展

青光眼(glaucoma)是一组具有特征性视神经损害和视野缺损的眼病,在临床上常常表现为视力减退、眼部胀痛伴头痛等症状,是一种致盲率居第二位的不可逆性眼病.青光眼视神经损伤有一定的遗传倾向,造成视神经凹陷性萎缩及视野不同程度缺损这两种结局的危险因素有多种,其中致盲的主要原因包括进行性视神经节损害、病理性眼压升高等.所以在青光眼的治疗中一方面要考虑降低眼压,另一方面还要保护好视神经.本文将从视神经损害的机制、影响因素、分级方法、视神经相关检测指标及其在临床上相关仪器应用、治疗等方面进行综述.

飞秒激光辅助角膜移植术的护理

总结32例飞秒激光辅助角膜移植术患者的护理,认为做好心理护理、术前完善眼部检查和做好充分的准备,术后严密观察敷料、眼压和角膜植片的情况,做好特殊体位和角膜接触镜的护理,并做好出院指导是提高手术的成功率及预防并发症的关键.

No blinding trachoma in Guangxi, China

In 2005,Boost and Cho reported a high incidence of trachoma in rural areas of Guangxi,China (1).Ten years later,active trachoma has been controlled in this province in southern China.